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The tree-borne fruit known as jackfruit (Artocarpus heterophyllus Lam) exists as the biggest fruit in the world because of its incredible size and weight. The native fruit supports numerous health advantages because of its high protein content along with fibers, vitamins A, vitamins C and antioxidants as well as mineral content. Nicotinic acid, riboflavin, folic acid, calcium, iron, magnesium and zinc constitute the essential components present in this fruit. A low GI (Glycemic Index) rating of jackfruit supports the management of blood sugar levels. The cancer-fighting capabilities of flavonoids along with phenolics, carotenoids and other substances found in it assist in antioxidant protection and lowering inflammation while providing anti-hypertensive benefits. These phytonutrients fight against oxidative stress, decrease inflammation and improve immunological function. Recent studies showed that jackfruit flour along with its seed flour applications bring important results in diabetes treatment while reducing chemotherapy negative impacts leading to better overall wellness.

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American Diabetes Association (ADA), 2019. Lifestyle management: Standards of medical care in diabetes - 2019. Diabetes Care 42(Suppl. 1), S46-S60. DOI: https://doi.org/10.2337/dc19-S005.

Patil, S.M., Manu, G., Ramya, C.M., Rajashekhara, S., Desai, S.M., Parameswaran, S., Ramu, R., 2025. Exploring jackfruit flour polyphenols as promising SGLT-2 inhibitors for hyperglycemia management. International Journal of Applied Pharmaceutics 17(1), 199-208. DOI: https://doi.org/10.22159/ijap.2025v17i1.52573.

Ranasinghe, R.A.S.N., Maduwanthi, S.D.T., Marapana, R.A.U.J., 2019. Nutritional and health benefits of jackfruit (Artocarpus heterophyllus Lam.): A review. International Journal of Food Science 2019, 4327183. DOI: https://doi.org/10.1155/2019/4327183.

Rao, A.G., Naik, K.S., Unnikrishnan, A.G., Joseph, J., 2021. Efficacy of green jackfruit flour as a medical nutrition therapy replacing rice or wheat in patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study. Nutrition & Diabetes 11, 18. DOI: https://doi.org/10.1038/s41387-021-00161-4.

Tripathi, K., Kumar, P., Kumar, R., Saxena, R., Kumar, A., Badoni, H., Goyal, B., Mirza, A.A., 2023. Efficacy of jackfruit components in prevention and control of human disease: A scoping review. Journal of Education and Health Promotion 12(1), 361. DOI: https://doi.org/10.4103/jehp.jehp_1683_22.