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<p style="text-align:justify"><span style="font-size:16px">CRISPR/Cas9 is a versatile genome-editing tool that has been used to investigate the function of genetic components, create genetically modified creatures, and conduct preclinical research on genetic illnesses. It is a new approach that may precisely and accurately change any section of any species without affecting other gene. In this article, we look at the molecular mechanism, applications, and problems of CRISPR/Cas9-mediated genome editing, as well as the future clinical pharmacological properties of CRISPR/Cas9.</span></p>
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<p style="text-align:justify"><span style="font-size:16px"><strong>Poonam Sharma</strong></span></p> <p style="text-align:justify"><span style="font-size:16px"><em>Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India</em></span></p> <p style="text-align:justify"><span style="font-size:16px"><strong>Parshant Kumar Sharma</strong></span></p> <p style="text-align:justify"><span style="font-size:16px"><em>Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India</em></span></p> <p style="text-align:justify"><span style="font-size:16px"><strong>Priya Sharma</strong></span></p> <p style="text-align:justify"><span style="font-size:16px"><em>Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India</em></span></p> <p style="text-align:justify"><span style="font-size:16px"><strong>O.P. Verma </strong></span></p> <p style="text-align:justify"><span style="font-size:16px"><em>Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India</em></span></p> <p style="text-align:justify"><span style="font-size:16px"><strong>Ashim Debnath<sup>*</sup></strong></span></p> <p style="text-align:justify"><span style="font-size:16px"><em>Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India</em></span></p>
How to cite
<p style="text-align:justify"><span style="font-size:14px">Sharma, P., Sharma, P.K., Sharma, P., Verma, O.P., Debnath, A., 2021. CRISPR-Cas9 Genome Editing System. <em>Biotica Research Today</em> 3(12), 1165-1166.</span></p>
Reference
<p style="text-align:justify"><span style="font-size:16px">Achary, V., Reddy, M.K., 2021. CRISPR-Cas9 mediated mutation in GRAIN WIDTH and WEIGHT2 (GW2) locus improves aleurone layer and grain nutritional quality in rice. <em>Scientific Reports</em> 11(1), 1-13.</span></p> <p style="text-align:justify"><span style="font-size:16px">Faber, N.R., McFarlane, G.R., Gaynor, R.C., Pocrnic, I., Whitelaw, C.B.A., Gorjanc, G., 2021. Novel combination of CRISPR-based gene drives eliminates resistance and localises spread. <em>Scientific Reports</em> 11(1), 1-15.</span></p> <p style="text-align:justify"><span style="font-size:16px">Sabit, H., Abdel-Ghany, S., Tombuloglu, H., Cevik, E., Alqosaibi, A., Almulhim, F., Al-Muhanaa., 2021. A New insights on CRISPR/Cas9-based therapy for breast cancer. <em>Genes and Environ</em> 43, 15.</span></p> <p style="text-align:justify"><span style="font-size:16px">Zhang, F., Wen, Y., Guo, X., 2014. CRISPR/Cas9 for genome editing: progress, implications and challenges. <em>Human Molecular Genetics</em> 23(R1), R40-R46.</span></p>
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