Abstract

Aquaculture has emerged as a vital solution to meet the global demand for animal protein, offering a highly efficient means of producing easily digestible and nutritious protein. Increased fish demand intensified aquaculture systems, which face several challenges, including stress, environmental degradation frequent disease outbreaks. To mitigate disease risks, antibiotics synthetic chemicals are often overused in aquaculture, contributing to the emergence of antimicrobial resistance (AMR) and long-term soil and water quality degradation. A sustainable approach to address these challenges is needed, aligning with the One Health framework by reducing reliance on antibiotics and chemicals. Plant-based bioactive compounds are gaining attention due to their potential to support the health and growth of aquatic species. Ferulic acid (FA), a plant phenolic compound, has shown considerable promise. This compound possesses antioxidant, growth-promoting, anti-inflammatory, wound-healing antimicrobial properties, making it a suitable alternative for enhancing aquaculture productivity. Research has demonstrated that FA promotes growth, alleviates stress, enhances metabolism supports muscle growth in various freshwater and brackish-water species, including Common carp, Trout, GIFT, Nile tilapia, White leg prawn, hybrid grouper, etc. Additionally, it boosts antioxidant potential, helping aquatic species combat oxidative stress in intensified farming systems. However, while the initial findings are promising, further scientific studies are essential to standardize appropriate dosages, understand the underlying mechanisms evaluate potential negative effects. Through comprehensive research, the full potential of Ferulic acid can be harnessed, contributing to sustainable disease management and improved health outcomes in aquaculture.